After PhD I had a stint as a research associate on a cellular immunology project “Human T-cell responses to Japanese encephalitis virus”.
I have set up laboratory evolution experiments with E. coli under prolonged stationary-phase starvation. The broader research questions include: What is the spectrum of mutations that get selected in predominant nutrient stress? Is there an order in which these mutations accumulate? Are there limited/fixed route/s towards a fitness peak? Of late, I have been interested in understanding the role of small RNA in adaptive evolution.
One of the incentives of being in research is that you get to be a detective...“You know my method. It is founded upon the observation of trifles.”-Sherlock Holmes.
1. Chib S, Mahadevan S. Involvement of the global regulator H-NS in the survival of Escherichia coli in stationary phase. Journal of Bacteriology. 194: 5285-5293. 2012.